ABSTRACT
Objective:To analyze the horizontal scientific research projects from 2015 to 2019 by the provincial Centers for Disease Control and Prevention (CDC) in China, and to compare the regional differences, in order to provide the suggestion on the scientific management of CDC.Methods:The horizontal scientific research projects from 2015 to 2019 were retrospectively analyzed by questionnaire survey. Multiple linear regression models were adopted to examine the trend, and variance analyses were used to test the differences in horizontal scientific research projects among the Eastern, Central, and Western regions.Results:From 2015 to 2019, provincial CDC have received RMB 124.3 million of horizontal scientific research project funds totally, of which 51.9% were funded by enterprises, and 86.9% were undertaken by provincial CDC themselves. There were no statistical significance in the change of research project funds obtained by provincial CDC ( F=0.46, P = 0.764) during this period.The number of horizontal scientific research projects undertook or participated by provincial CDC in the Eastern region were more than that of the Central and Western region ( F = 5.85, P = 0.004; F = 5.03, P = 0.008). Conclusions:The horizontal scientific research projects obtained by the provincial CDC remained stable in recent years while distribution was unbalanced in the region areas. It is suggested to innovate the management mode of scientific research projects with strengthening the trans-agency, trans-department and trans-regional cooperation.
ABSTRACT
Objective@#To investigate the main risk factors of hepatitis B virus (HBV) infection in Karamay, to provide scientific basis for hepatitis B prevention and control.@*Methods@#Hepatitis B patients treated in Karamay Central Hospital in 2014 were selected as the case group, and the HBsAg negative cases were selected as control group by case control study method according to the same hospital, gender, age and other factors. Questionnaire survey was conducted and serological markers of HBV infection were detected.@*Results@#Multivariate analysis showed that family members of patients with HBV infection, HBV infection markers detection, aesthetic treatment caused trauma history (e.g., eyebrow tattoo, Tattoo, eyeliner tattoo, piercing ears), and no hepatitis B vaccination history were the main risk factors of HBV infection in Karamay currently.@*Conclusions@#The risk factors of HBV infection in Karamay population still exist. The propaganda and education of hepatitis B prevention knowledge in the public should be improved in the future. Changing adverse lifestyle and the timely initiatiation of hepatitis B vaccination are important measures to control HBV infection.
ABSTRACT
105 copies/mL would develop liver-related complications, such as cirrhosis, hepatocellular carcinoma and liver failure. Available evidences indicate that control of HBV replication with antiviral drugs can decrease the incidence of these complications and mortality.